Miniony tydzień na rynku złotego upłynął pod znakiem lekkiej korekty notowań polskiej waluty.
Kończący się tydzień rozpoczął się od umocnienia złotego, ale przez większą jego część na rynku lekką przewag ę mieli sprzedający.
Kluczowe znaczenie będą mieć dzisiaj dane o sprzedaży detalicznej w USA (godz. 14:30) i nastrojach konsumenckich Uniw. Michigan (godz. 15:55).![File:Carlos Ghosn.jpg [en]](/en/wiki/File:Carlos_Ghosn.jpg.html){kind=link}
Ginsenoside
From Wikipedia, the free encyclopedia
| Ginsenoside Rg1 | |
|---|---|
 |
|
|
6,20-Bis(β-D-glucopyranosyl)-(3β,6α,12β,20S)-3,6,12,20-tetrahydroxydammar-24-ene
|
|
|
other names
Ginsenoside A2
Panaxoside A Sanchinoside C1 |
|
| Identifiers | |
| CAS number | 22427-39-0  |
| ChemSpider | 390498 |
| EC-number | 244-989-9 |
| InChI |
1/C42H72O14/c1-20(2)10-9-13-42(8,56-37-34(52)32(50)30(48)25(19-44)55-37)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28-,29+,30+,31-,32-,33+,34+,35-,36+,37-,39+,40+,41+,42-/m0/s1
|
| Properties | |
| Molecular formula | C42H72O14 |
| Molar mass | 801.01 g/mol |
| (what is this?) (verify) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
|
| Infobox references | |
Ginsenosides are a class of steroid glycosides, and triterpene saponins, found exclusively in the plant genus Panax (ginseng). Ginsenosides have been the target of research, as they are viewed as the active compounds behind the claims of ginseng's efficacy. Because ginsenosides appear to affect multiple pathways, their effects are complex and difficult to isolate.
Ginsenosides are separated by column chromatography. Ginsenoside content can vary widely depending on species, location of growth, and growing time before harvest.
The root, the organ most often used, contains saponin complexes. These are often split into two groups: the Rb1 group (characterized by the protopanaxadiol presence : Rb1, Rb2, Rc and Rd) and the Rg1 group (propanaxatriol: Rg1, Re, Rf, and Rg2).[1]
Contents |
[edit] Rb1 group
[edit] Rb1
Appears to be most abundant in Panax quinquefolius (American Ginseng).
Rb1 seems to affect the reproductive system in animal testicles.
Recent research shows that Rb1 affects rat embryo development[2] and has teratogenic effects, causing birth defects.[3]
Another study shows that Rb1 may increase testosterone production in male rats indirectly through the stimulation of the luteinizing hormone. Traditional Chinese medicine asserts that Panax quinquefolius promotes yin in the body.
It also inhibits chemoinvasion and angiogenesis.
[edit] Rb2
[edit] Rc
Ginsenoside-Rc is a steroid molecule that can be found in the ginseng plant and is recognized for producing more sedative related results than other ginsenosides, such as ginsenoside-Re or ginsenoside-Rg.
In one study on breast cancer and different ginsenosides, it was found that ginsenoside-Rc was capable of inhibiting the growth of these cancer cells. This suggests that there is a possibility that ginsenoside-Rc may have effects that prevent or limit the development of breast cancer.[4]
An experiment was performed on Caenorhabditis elegans and their survival in a cholesterol-absent medium with the presence of ginsenoside-Rc. While the lack of cholesterol for Caenorhabditis elegans is expected to reduce the lifetime of the worm, results proved otherwise. The consumption of ginsenoside-Rc had elongated the normal life span of the worm. [5]
A further study was also able to demonstrate a possible effect of ginsenoside-Rc on the motility of sperm. Data from this experimentation showed a significant increase in motility when the sperm was in a ginsenoside-Rc solution. [6]
[edit] Rd
[edit] Rg1 group
[edit] Re
[edit] Rf
Present in Panax ginseng; not present in Panax quinquefolius.[7]
[edit] Rg1
Appears to be most abundant in Panax ginseng (Chinese/Korean Ginseng). Improves spatial learning and increase hippocampal synaptophysin level in mice, plus estrogen-like activity (which could account for the boosting of "yin" theory).
[edit] Rg2
Ginsenoside Rg2 appears also to be abundant in Panax ginseng and could protect memory impairment via anti-apoptosis in a rat model with vascular dementia.[8][9]
Rg2 is a α-L-Rha→β-D-Glc glycoside of panaxatriol.
[edit] Metabolism
M1 (20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol) is a ppd-type monoglucoside ginsenoside metabolized by intestinal bacteria in humans.
[edit] References
- ^ Panax quinquefolium - Ginseng, American page on www.wrc.net
- ^ [1]
- ^ Chan LY, Chiu PY, Lau TK. Hum Reprod. 2003 Oct;18(10):2166-8. An in-vitro study of ginsenoside Rb1-induced teratogenicity using a whole rat embryo culture model
- ^ [2]
- ^ [3]
- ^ [4]
- ^ [5]
- ^ Panax ginseng ginsenoside-Rg2 protects memory impairment via anti-apoptosis in a rat model with vascular dementia
- ^ Determination of ginsenoside Rf and Rg2 from Panax ginseng using enzyme immunoassay.
[edit] External links
- European Society of Human Reproduction and Embryology Researchers caution over using ginseng in early pregnancy
- Stimulation of the secretion of luteinizing hormone by ginsenoside-Rb1 in male rats
- Ginsenosides as Quality Indicators in Woods-grown American Ginseng
- Title: The Effect of Production Practices on the Quality of Ginseng Roots
- The King's University College Biology Department
 |
This biochemistry article is a stub. You can help Wikipedia by expanding it. |
 |
This organic chemistry article is a stub. You can help Wikipedia by expanding it. |